The data in this paper shows how astrocytes as essential contributors to information processing and cognitive behavior. In particular, the selective expression of tetanus neurotoxin (TeNT) in astrocytes significantly reduced the duration of carbachol-induced gamma oscillations in hippocampal slices. The results support a key role for gamma oscillations in recognition memory utilizing an in vivo model.

PUBLICATION: Proceedings of the National Academy of Sciences (2014)

AUTHORS: Hosuk Sean Leea, Andrea Ghetti, António Pinto-Duartec, Xin Wang, Gustavo Dziewczapolski , Francesco Galimi, Salvador Huitron-Resendiz , Juan C. Piña-Crespoa, Amanda J. Roberts , Inder M. Verma, Terrence J. Sejnowski, and Stephen F. Heinemann