This paper describes the next steps for a human-based approach to disease supported by computational methodologies as described at a Workshop on Computational Cardiovascular Science. The main ideas outlined show a shift towards human-based methodologies spurred by advances in computational approaches to complement in vitro, in vivo and ex vivo experimental and clinical data as an integral part of pharmacology and medicine.

PUBLICATION: European Society of Cardiology (2017)

AUTHORS: Blanca Rodriguez, Annamaria Carusi, Najah Abi-Gerges, Rina Ariga, Oliver Britton, Gil Bub, Alfonso Bueno-Orovio, Rebecca A.B. Burton, Valentina Carapella, Louie Cardone-Noott, Matthew J. Daniels, Mark R. Davies, Sara Dutta, Andre Ghetti, Vicente Grau, Stephen Harmer, Ivan Kopljar, Pier Lambiase, Hua Rong Lu, Aurore Lyon, Ana Minchole, Anna Muszkiewicz, Julien Oster, Michelangelo Paci, Elisa Passini1, Stefano Severi, Peter Taggart, Andy Tinker, Jean-Pierre Valentin, Andras Varro, Mikael Wallman and Xin Zhou