Phenotypic Profiling of Human Dorsal Root Ganglion Neurons

In this study, we report a new approach for studying the phenotypic profile of human DRG neurons in culture, based on the responses to electrical field stimulation, chemical irritants (capsaicin and AITC) and cold buffer. This methodology provides valuable tools for studying the properties of human sensory neurons and for investigating the activity of new analgesic drugs in the context of pathological states. 

AUTHORS: Jingming Zhang, Yannick Miron, Guy Page, Bryan Copits, Steve Davidson, Paul Miller, Robert W. Gereau, IV and Andre Ghetti