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Cardiac Publications

Ion Channel Expression & Electrophysiology of Singular Human (Primary & Induced Pluripotent Stem Cell-Derived) Cardiomyocytes C. Schmid, N. Abi-Gerges, M. Leitner, D. Zellner and G. Rast., CELLS, 2021
Cardiotoxic Potential of Hydroxychloroquine, Chloroquine and Azithromycin in Adult Human Primary Cardiomyocytes N. Abi-Gerges, P. Jordaan, A. Ghetti, P. Miller, L. Urban, B. Dumotier, et al.
Multiparametric Mechanistic Profiling of Inotropic Drugs in Adult Human Primary Cardiomyocytes N. Abi-Gerges, T. Indersmitten, W. Nguyen, A. Ghetti, P. Miller, et al., Nature Scientific Reports, 2020
Discovery & Characterization of ORM-11372, A Unique & Positively Inotropic Sodium-Calcium Exchanger/Inhibitor L. Otsomaa, J. Levijoki, N. Abi-Gerges, A. Ghetti, P. Miller, G. Page, et al.
Computational Cardiology & Risk Stratification for Sudden Cardiac Death N. Abi-Gerges, A. Hill, M. Perry, et al., White Paper, 2016
Human-Based Approaches to Pharmacology and Cardiology: An Interdisciplinary and Intersectional Workshop N. Abi-Gerges, B. Rodriguez, et al., Europace, European Society of Toxicology, 2016
Quantitative Comparison of Effects of Dofetilide, Sotalol, Quinidine & Verpamil Between Human Ex Vivo Trabeculae & In Silico Ventricular Models Incorporating Inter-Individual Action Potential Variability N. Abi-Gerges, G. Page, P. Miller, A. Ghetti, et al. Frontiers in Physiology, 2017
Human Ex-Vivo Action Potential Model for Pro-Arrhythmia Risk Assessment A. Ghetti, P. Miller, G. Page, Y. Mirron, et al., Journal of Pharmacological & Toxicological Methods, 2016
Adult Human Primary Cardiomyocyte-Based Model for Simultaneous Prediction of Drug-Induced Inotropic & Pro-Arrhythmia Risk A. Ghetti, P. Miller, N. Abi-Gerges, G. Page, et al., Frontiers in Physiology, 2017
FDA Workshop on Improving Cardiotoxicity Assessment with Human-Relevant Platforms N. Abi-Gerges, M. Brock, J. Wu, et al., Circulation Research, 2019
Human Purkinje in Silico Model Enables Mechanistic Investigations into Automaticity and Pro-Arrhythmic Abnormalities N. Abi-Gerges, B. Rodriguez, S. Severi, et al., Journal of Molecular and Cellular Cardiology, 2020
Adult Human Primary Cardiomyocytes: An Integrative Translational Model for Preclinical Drug Testing N. Nguyen, N. Abi-Gerges, P. Ratchada, G. Page, Y. Miron, , P. Miller and A. Ghetti. 2017
Label-Free Imaging of Atherosclerotic Plaques Using Third-Harmonic Generation Microscopy D. Small, J. Jones, A. Ghetti, P. Miller, I. Tendler, et al. Biometrics Optics Express. 2018
Action Potential Recording and Pro-Arrhythmia Risk Analysis in Human Ventricular Trabeculae G. Page, N. Abi-Gerges, A. Ghetti, P. Miller, H. Vargas, et al. Frontiers in Physiology. 2018

Cardiac Webinars

Human Models for Translational Science: Late Sodium Current in the Human Heart Presented by Dr. Najah Abi-Gerges
Myocardial Slices: A Novel Discovery Model to Study the Biology of the Human Heart Presented by Dr. Cesare Terracciano
Human Primary Cardiomyocyte Model for Predicting Inotropes Presented by Dr. Najah Abi-Gerges
Evolving Concepts of Atrial Fibrillation Mechanisms: Relevance to Therapeutic Innovation Presented by Dr. Najah Abi-Gerges
Discovery & Characterization of ORM-11372: Implications for Heart Failure Drug Discovery Presented by Jouko Levijoki
Human Heart Slices as the Next Generation of Cardiotoxicity Testing Platform Presented by Dr. Tamer Mohamed
The Role of BAG3 in Dilated Cardiomyopathy Presented by Dr. Arthur Feldman
Arrhythmogenic & Antiarrhythmic Actions of Late Sustained Sodium Current in the Adult Human Heart Presented by Dr. Najah Abi-Gerges
Scientist.com’s Cutting Edge Conversations: Challenges in Sourcing Human Biosamples Presented by Dr. Richard Kondo
Preclinical Assessment of Native Human Cardiomyocytes Provide Translational Value in Drug Development Presented by Dr. Laszlo Urban & Dr. Najah Abi-Gerges

Cardiac Posters

Action Potential Recording and Pro-Arrhythmia Risk Analysis in Human Ventricular Trabeculae
Human Primary Cardiomyocyte Model for Simultaneous Prediction of Drug-Induced Inotropic and Pro-Arrhythmia Risk
Effect of Ozanimod on Action Potential Parameters in Adult Human Purkinje Fibres
A Human Ex-Vivo Contractility-Based Assay for the Simultaneous Prediction of Drug-Induced Inotropic and Pro-Arrhythmia Risk
Adult Human Primary Cardiomyocyte-Based Platform for the Profiling of Positive Inotropes with Potential to Treat Heart Failure
A Human Cardiomyocyte-Based Platform for the Profiling of Drug Effects on Cardiac Contractility: Predicting Inotropic Mechanisms of Action
A Human Cardiomyocyte-Based Platform for the Profiling of Positive Inotropes with Potential to Treat Heart Failure
Late Sustained Sodium Current (INa1L) in Adult Human Primary Cardiomyocytes
Adult Human Primary Cardiomyocytes: An Integrative Translational Model for Preclinical Drug Testing

Cardiac Brochures

Adult Human Heart Tissue Brochure
AnaBios CardioPRIME Brochure