Publications and Resources

Publications and Resources 2017-12-08T01:43:41+00:00


Enright H. A., Felix S. H., Fischer N. O., Mukerjee E. V., Soscia D., Mcnerney M., Kulp K., Zhang J., Page G., Miller P., Ghetti A., Wheeler E. K. and Pannu S. (2016) Long-term non-invasive interrogation of human dorsal root ganglion neuronal cultures on an integrated microfluidic multielectrode array platform. Analyst; DOI: 10.1039/C5AN01728A.

Davidson S, Golden JP, Copits BA, Ray PR, Vogt SK, Valtcheva MV, Schmidt RE, Ghetti A, Price T, Gereau RW (2016) Group II mGluRs suppress hyperexcitability in mouse and human nociceptors. Pain: PMID: 27218869.

Castro J, Harrington AM, Garcia-Caraballo S, Maddern J, Grundy L, Zhang J, Page G, Miller PE, Craik DJ, Adams DJ, Brierley SM (2016) α-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABAB receptors. Gut; 10.1136/gutjnl-2015-310971.

Li Y, Adamek P, Zhang H, Esteves Tatsui C, Rhines LD, Mrozkova P, Li Q, Kosturakis AK, Cassidy RM, Harrison DS, Cata JP, Sapire K, Zhang H, Kennamer-Chapman RM, Jawad AB, Ghetti A, Yan Y, Palecek J, Dougherty PM (2015) The Cancer Chemotherapeutic Paclitaxel Increases Human and Rodent Sensory Neuron Responses to TRPV1 by Activation of TLR4. Journal of Neuroscience, 35 (39): 13487-13500; doi:10.1523/JNEUROSCI.1956-15.2015

Copits B, Davidson S, Zhang J, Page G, Ghetti A, Gereau RW (2015) Human sensory neurons: cellular excitability, sensitization, and ion channel conductances. Journal of Pain 16(4): S60. DOI: 10.1016/j.jpain.2015.01.256

Davidson S, Copits BA, Zhang J, Page G, Ghetti A, Gereau RW 4th. (2014) Human sensory neurons: Membrane properties and sensitization by inflammatory mediators. Pain; S0304-3959(14)00306-6. doi: 10.1016/j.pain.2014.06.0173)

Arneric SP, Zhang J, Miller P, Rankovic R, Hahn PJ, Gernert DL, Ghetti A (2014) Action of biased-mor agonists to inhibit depolarization-induced calcium mobilization in cultured human DRG neurons. Abstract IASP Meeting

Zhang J, Page P, Enright H, Mcnerney W, Mukerjee E, Wheeler E, Pannu S, Kulp K, Qian F, Miller P and Ghetti A (2014) Gadolinium-induced activation of nociceptors in human DRG neuronal-glial cultures. Abstract IASP Meeting

Arneric SP, Laird JM, Chappell AS, Kennedy JD. (2014) Tailoring chronic pain treatments for the elderly: are we prepared for the challenge? Drug Discov Today; 19: 8-17.

Davidson S, Golden JP, Page G, Zhang J, Ghetti A, and Gereau RW (2013) Sensory neuron hyperexcitability is prevented by group 2 metabotropic glutamate receptors in mouse and human metabotropic glutamate receptors in mouse and human. Poster at NIH Pain Meeting.

Tate SN, Rugiero F, Derjean D, Panchenko VA, Owen D, Ghetti A, Bannister K, Thakur M, Dickenson AH, Miller P, Morisset V (2012) Carbamazepine and CNV1427400 exhibit similar pharmacology in recombinant systems, rat and human native DRGs. Poster at Society for Neurosciensce Meeting.

Payne L, Panchenko VA, Ghetti A, Alexandrou A, Miller PE, Stevens E (2012) Biophysical and pharmacological characterisation of native human Nav1.8 channels from isolated dorsal root ganglia (DRG). Poster at Biophysical Society Meeting.

Alexandrou A, Turner J, Payne E, Cox PJ, Panchenko VA, Ghetti A, Prime R, Doyle R, Chapman M, Maron B, Miller, PE, Butt R, Stevens E (2012) Nav1.7 ios the dominant subtype underlying TTX-s currents in small diameter mouse & human DRGs. Society for Neuroscience Meeting.


Guy Page, Phachareeya Ratchada, Yannick Miron, Guido Steiner, Andre Ghetti, Paul E. Miller, Jack A. Reynolds, Ken Wang, Andrea Greiter-Wilke, Liudmila Polonchuk, Martin Traebert, Gary A. Gintant, Najah Abi-Gerges Human ex-vivo action potential model for pro-arrhythmia risk assessment. J. Pharmacol Toxicol Methods; 81: 183-195

Rodriguez B, Carusi A, Abi-Gerges N, Ariga R, Britton O, Bub G, Bueno-Orovio A, Burton R, Carapella V et al., (2015) Human-based approaches to pharmacology and cardiology: an interdisciplinary and intersectorial workshop. Europace, pii: euv320

Reynolds J, Ghetti A, Miller P (2013) A robust and reliable ex vivo method for assessing cardiac repolarization using “living” human hearts. J Pharmacol Toxicol Method; 68: e167)


Lee HS, Ghetti A, Pinto-Duarte A, Wang X, Dziewczapolski G, Galimi F, Huitron-Resendiz S, Piña-Crespo JC, Roberts AJ, Verma IM, Sejnowski TJ, Heinemann SF. (2014) Astrocytes contribute to gamma oscillations and recognition memory. Proc Natl Acad Sci U S A.; 111 (32): E3343-522)


Learn how AnaBios’ proprietary human-based technology has helped top pharma and biotech firms improve the safety and efficacy of their novel compounds throughout the drug discovery process.

To download our most recent posters, please click on one of the buttons below.

AnaBios Ex Vivo Human Trabeculae APD Poster   SPS 2017 Adult Human Primary Cardiomyocyte Validation Poster 

Effect of Ozanimod on Action Potential Parameters in Adult Human Purkinje Fibres